Evolutionary cell biology comes of age

Gautam Dey, Lillian Fritz-Laylin, Snezhana Oliferenko, Eelco C. Tromer · 2024

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Description

Evolutionary cell biology, the study of how cells themselves evolve and diversify, is coming into its own. The four authors trace its roots to Darwin and Haeckel, its long eclipse by a few tractable model organisms, and its revival through genomics, imaging, experimental evolution, and phylogenetics. The head dates this Perspective to 2025, though the catalog lists 2024.

They name four challenges for the field. It must fuse cell biology with evolutionary theory and experiments, covering adaptive and non-adaptive change alike. It must bridge the genotype-phenotype gap. It must develop new model systems that capture the true diversity of cell mechanisms. And it must weave in ecology, so environmental forces enter the account of cell form. Meeting them, the authors argue, would reveal rules of cellular complexity and adaptation across the tree of life.

Catalog record

CREATORGautam Dey, Lillian Fritz-Laylin, Snezhana Oliferenko, Eelco C. Tromer
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE39 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12752495

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