Enhanced lubricin secretion by human synovial mesenchymal stem cells compared to adipose mesenchymal stem cells
Takuya Takakuwa, Kentaro Endo, Nobutake Ozeki, Yusuke Nakagawa, Hideyuki Koga, Makoto Tomita, Ichiro Sekiya · 2025
Read Enhanced lubricin secretion by human synovial mesenchymal stem cells compared to adipose mesenchymal stem cells by Takuya Takakuwa, Kentaro Endo, Nobutake Ozeki, Yusuke Nakagawa, Hideyuki Koga, Makoto Tomita, Ichiro Sekiya (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12752376.txt.
Description
BackgroundMesenchymal stem cell (MSC) therapy has emerged as a promising treatment option for knee osteoarthritis. Adipose MSCs are commonly used due to their easy accessibility; however, synovial MSCs have demonstrated a superior capacity for cartilage matrix synthesis. The mechanism underlying this difference in therapeutic efficacy may involve lubricin, a crucial glycoprotein that maintains joint lubrication and protects cartilage.
Catalog record
| CREATOR | Takuya Takakuwa, Kentaro Endo, Nobutake Ozeki, Yusuke Nakagawa, Hideyuki Koga, Makoto Tomita, Ichiro Sekiya |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |