Survival patterns and mutation profiles in never- and light-smokers with stage IV NSCLC
Kholoud Alqasem, Sakhr Alshwayyat, Salsabeel Aljawabrah, Karam Maraqa, Alaa BanyAmer, Aysheh Al-Khawaja, Bayan Sheikh Ali, Shahed Al-atiyat, Rahaf Turab, Rana Elmalahi, Ala’aldin Eqleem, Sumaiah Alnaimat, Ahmad BanyAmer, Marwa Alshatti, Zaid Omari, Mohammad Abu Shattal · 2025
Read Survival patterns and mutation profiles in never- and light-smokers with stage IV NSCLC by Kholoud Alqasem, Sakhr Alshwayyat, Salsabeel Aljawabrah, Karam Maraqa, Alaa BanyAmer, Aysheh Al-Khawaja, Bayan Sheikh Ali, Shahed Al-atiyat, Rahaf Turab, Rana Elmalahi, Ala’aldin Eqleem, Sumaiah Alnaimat, Ahmad BanyAmer, Marwa Alshatti, Zaid Omari, Mohammad Abu Shattal (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12752286.txt.
Description
Kholoud Alqasem and co-authors compare survival and tumor mutations in lung cancer patients who never or barely smoked, in a 2025 study. Up to fifteen percent of this cancer arises in never-smokers. Data from the Middle East are scarce. The team reviewed stage IV cases treated at a Jordanian center from 2015 to 2023.
Of 190 patients, 159 had never smoked and 31 were light smokers. Never-smokers were mostly women. Light smokers showed a different profile. Survival patterns and gene changes were compared between the groups. Standard risk models built on heavy smokers may miss what drives cancer in this group. Regional data help clinics plan testing and treatment for them.
Catalog record
| CREATOR | Kholoud Alqasem, Sakhr Alshwayyat, Salsabeel Aljawabrah, Karam Maraqa, Alaa BanyAmer, Aysheh Al-Khawaja, Bayan Sheikh Ali, Shahed Al-atiyat, Rahaf Turab, Rana Elmalahi, Ala’aldin Eqleem, Sumaiah Alnaimat, Ahmad BanyAmer, Marwa Alshatti, Zaid Omari, Mohammad Abu Shattal |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |