Investigation of androgen receptor expression in urothelial carcinoma of the bladder

André Luís Nunes Avelino, Felipe Dias Gonçalves, Jhonas Nathanael Menezes Ferreira, Gislane Rocha Vasconcelos, Conceição Aparecida Dornelas · 2025

Read Investigation of androgen receptor expression in urothelial carcinoma of the bladder by André Luís Nunes Avelino, Felipe Dias Gonçalves, Jhonas Nathanael Menezes Ferreira, Gislane Rocha Vasconcelos, Conceição Aparecida Dornelas (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12752205.txt.

Description

André Luís Nunes Avelino and co-authors tested whether a hormone receptor shows up in bladder cancers and tracks with the disease's features, in a 2025 study. The androgen receptor helps drive prostate growth, and hints suggest it may also matter in bladder cancer, which strikes men far more often. The team reviewed patients treated by bladder tumor resection between 2016 and 2021 and stained each tumor for the receptor.

Nearly every case, ninety-seven and a half percent, showed low receptor levels. High expression appeared in barely one percent, with a small indeterminate slice. Expression tied to nothing: not sex, age, smoking, tumor number or size, vessel invasion, grade, or stage. The authors conclude the receptor's value as a bladder cancer marker is unproven and needs deeper study. A honest null result, they imply, still saves others from a blind alley.

Catalog record

CREATORAndré Luís Nunes Avelino, Felipe Dias Gonçalves, Jhonas Nathanael Menezes Ferreira, Gislane Rocha Vasconcelos, Conceição Aparecida Dornelas
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE17 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12752205

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