Closing the evidence loop—membrane-lipid homeostasis and vesicular transport link DEHP exposure to endometriosis

Yonggang Dai, Lu Zhang, Tian Wang, Hao Liu, Wenyi Yang, Hongya Wang · 2025

Read Closing the evidence loop—membrane-lipid homeostasis and vesicular transport link DEHP exposure to endometriosis by Yonggang Dai, Lu Zhang, Tian Wang, Hao Liu, Wenyi Yang, Hongya Wang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12751832.txt.

Description

BackgroundThe causal bridge from environmental exposure to endometriosis (Ems) biology remains incompletely defined. Di(2-ethylhexyl) phthalate (DEHP) is repeatedly implicated in elevated Ems risk, yet actionable molecular anchors linking exposure to phenotype are scarce.MethodsWe established a multi-layered pipeline centered on DEHP. Comprehensive in silico target prediction across ChEMBL, PharmMapper, and SwissTargetPrediction yielded 1364 de-duplicated candidate proteins.

Catalog record

CREATORYonggang Dai, Lu Zhang, Tian Wang, Hao Liu, Wenyi Yang, Hongya Wang
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12751832

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