Closing the evidence loop—membrane-lipid homeostasis and vesicular transport link DEHP exposure to endometriosis
Yonggang Dai, Lu Zhang, Tian Wang, Hao Liu, Wenyi Yang, Hongya Wang · 2025
Read Closing the evidence loop—membrane-lipid homeostasis and vesicular transport link DEHP exposure to endometriosis by Yonggang Dai, Lu Zhang, Tian Wang, Hao Liu, Wenyi Yang, Hongya Wang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12751832.txt.
Description
BackgroundThe causal bridge from environmental exposure to endometriosis (Ems) biology remains incompletely defined. Di(2-ethylhexyl) phthalate (DEHP) is repeatedly implicated in elevated Ems risk, yet actionable molecular anchors linking exposure to phenotype are scarce.MethodsWe established a multi-layered pipeline centered on DEHP. Comprehensive in silico target prediction across ChEMBL, PharmMapper, and SwissTargetPrediction yielded 1364 de-duplicated candidate proteins.
Catalog record
| CREATOR | Yonggang Dai, Lu Zhang, Tian Wang, Hao Liu, Wenyi Yang, Hongya Wang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |