Coronavesicle-engineered hydrogel sequential photothermal-immunometabolic therapy reprograms tissue microenvironment for diabetic-infected wounds healing
Bodeng Wu, Shan Lin, Qi Xiu, Mingzhen Zhong, Yiyao Huang, Zhenxun Wang, Xiuhua Wu, Jiangang Mei, Shuhan Liu, Liping Liu, Bo Li, Weilun Pan, Lei Zheng · 2025
Read Coronavesicle-engineered hydrogel sequential photothermal-immunometabolic therapy reprograms tissue microenvironment for diabetic-infected wounds healing by Bodeng Wu, Shan Lin, Qi Xiu, Mingzhen Zhong, Yiyao Huang, Zhenxun Wang, Xiuhua Wu, Jiangang Mei, Shuhan Liu, Liping Liu, Bo Li, Weilun Pan, Lei Zheng (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12751733.txt.
Description
Diabetic wounds that catch infection often heal slowly, because germs and a disordered wound bed block repair. Bodeng Wu and co-authors report a 2025 study of a gel dressing built to treat such wounds in steps. The gel carries tiny bubbles made from plant material, coated with polyphenols, and it answers to near-infrared light.
The bubbles stick to germ surfaces first, so light-driven heat kills bacteria where they sit. The heat then bursts the bubbles and frees the active plant compounds inside. Once the germs are cleared, those compounds help skin cells grow, calm oxidative stress, and shift immune cells away from a harmful state. Tests in dishes and in animals showed good healing results, and the authors offer the design as a path for future wound care.
Catalog record
| CREATOR | Bodeng Wu, Shan Lin, Qi Xiu, Mingzhen Zhong, Yiyao Huang, Zhenxun Wang, Xiuhua Wu, Jiangang Mei, Shuhan Liu, Liping Liu, Bo Li, Weilun Pan, Lei Zheng |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |