EEG-based detection of early functional brain changes in subjective cognitive decline: a prospective cohort study
Nayoung Ryoo, Ji Yong Park, Chunghwee Lee, SeongHee Ho, Yun Jeong Hong, Jee Hyang Jeong, Kee Hyung Park, Min Jeong Wang, Seong Hye Choi, SangYun Kim, Young Chul Youn, Euijin Kim, Sungkean Kim, Dong Won Yang · 2025
Read EEG-based detection of early functional brain changes in subjective cognitive decline: a prospective cohort study by Nayoung Ryoo, Ji Yong Park, Chunghwee Lee, SeongHee Ho, Yun Jeong Hong, Jee Hyang Jeong, Kee Hyung Park, Min Jeong Wang, Seong Hye Choi, SangYun Kim, Young Chul Youn, Euijin Kim, Sungkean Kim, Dong Won Yang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12751729.txt.
Description
People who feel their memory slipping, while tests still pass them, may already carry Alzheimer's seeds. Nayoung Ryoo and co-authors followed in 2025 one hundred twenty such adults for two years, recording brain waves and sorting them by amyloid status. Those with amyloid showed stronger slow waves and weaker alpha rhythm at both visits.
Machine learning models read the brain-wave patterns and separated the amyloid-positive group sharply, beating a model fed only personal details. Explanation tools showed which wave features drove the calls. The authors pitch EEG, cheap and painless, as a scalable early-warning screen before clear impairment appears.
Catalog record
| CREATOR | Nayoung Ryoo, Ji Yong Park, Chunghwee Lee, SeongHee Ho, Yun Jeong Hong, Jee Hyang Jeong, Kee Hyung Park, Min Jeong Wang, Seong Hye Choi, SangYun Kim, Young Chul Youn, Euijin Kim, Sungkean Kim, Dong Won Yang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |