Clinical efficacy and safety of eravacycline for the treatment of enterococcal infections: a subpopulation analysis

Sean R Van Helden, Ashlan J Kunz Coyne, Sara Alosaimy, Kyle C Molina, S Lena Kang-Birken, Justin Andrade, Madeline A King, Kimberly C Claeys, Athena L V Hobbs, Nicholson B Perkins III, Jazmin Agee, Alaina DeKerlegand, Mark Biagi, Michael P Veve, Serina Tart, Tristan Gore, Bruce M Jones, Benjamin M P · 2025

Read Clinical efficacy and safety of eravacycline for the treatment of enterococcal infections: a subpopulation analysis by Sean R Van Helden, Ashlan J Kunz Coyne, Sara Alosaimy, Kyle C Molina, S Lena Kang-Birken, Justin Andrade, Madeline A King, Kimberly C Claeys, Athena L V Hobbs, Nicholson B Perkins III, Jazmin Agee, Alaina DeKerlegand, Mark Biagi, Michael P Veve, Serina Tart, Tristan Gore, Bruce M Jones, Benjamin M P (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12751535.txt.

Description

Sean Van Helden and many colleagues published a 2025 analysis of an antibiotic called eravacycline against gut bacteria named enterococci. These bacteria cause common hospital infections with high death rates. Strains that resist key drugs, like vancomycin, are on the rise.

Eravacycline is a new member of the tetracycline family, approved for complex belly infections. The team pulled out the enterococcus cases from past trial data. They judged how well the drug cured these infections and how safe it was. Subgroup checks like this show where a drug's label may stretch. Doctors need sound options when standard drugs fail against resistant strains.

Catalog record

CREATORSean R Van Helden, Ashlan J Kunz Coyne, Sara Alosaimy, Kyle C Molina, S Lena Kang-Birken, Justin Andrade, Madeline A King, Kimberly C Claeys, Athena L V Hobbs, Nicholson B Perkins III, Jazmin Agee, Alaina DeKerlegand, Mark Biagi, Michael P Veve, Serina Tart, Tristan Gore, Bruce M Jones, Benjamin M P
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12751535

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