Efficacy and safety of periodontal initial therapy combined with intralesional betamethasone sodium phosphate injection under local anesthesia in managing erosive oral lichen planus: study protocol for a multi-center, split-mouth, randomized self-controlled trial
Huiwen Chen, Liran Shi, Qianhui Shang, Zihao Wei, Qiaozhen Yang, Yining He, Chenxi Li, Zengtong Zhou, Guoyao Tang, Hongying Sun, Gulinuer Awuti, Zhongchen Song, Linjun Shi · 2025
Read Efficacy and safety of periodontal initial therapy combined with intralesional betamethasone sodium phosphate injection under local anesthesia in managing erosive oral lichen planus: study protocol for a multi-center, split-mouth, randomized self-controlled trial by Huiwen Chen, Liran Shi, Qianhui Shang, Zihao Wei, Qiaozhen Yang, Yining He, Chenxi Li, Zengtong Zhou, Guoyao Tang, Hongying Sun, Gulinuer Awuti, Zhongchen Song, Linjun Shi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12751475.txt.
Description
Huiwen Chen and co-authors lay out a trial protocol for a painful mouth condition, in a 2025 paper. Erosive oral lichen planus eats at the gums and cheeks, and gum disease often travels with it; each seems to worsen the other. Steroid shots into the lesions help, but pairing them with deep gum cleaning under numbing had not been tested in a strict trial.
The split-mouth design treats one side of each patient's mouth with the combined plan and the other side with a comparison plan, so each person is their own control. Twenty-nine adults at five hospitals in China will take part. Healing, pain, and side effects will be tracked. A within-person design gives clean answers from few patients.
Catalog record
| CREATOR | Huiwen Chen, Liran Shi, Qianhui Shang, Zihao Wei, Qiaozhen Yang, Yining He, Chenxi Li, Zengtong Zhou, Guoyao Tang, Hongying Sun, Gulinuer Awuti, Zhongchen Song, Linjun Shi |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 85 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |