A systematic meta-review of interventions to prevent and manage delirium in the Intensive Care Unit: Part 1 – Pharmacological interventions
Katherine L Jones, Burak Kundakci, Andrew Booth, Louise Falzon, Ben Gibbison, Maria Pufulete · 2025
Read A systematic meta-review of interventions to prevent and manage delirium in the Intensive Care Unit: Part 1 – Pharmacological interventions by Katherine L Jones, Burak Kundakci, Andrew Booth, Louise Falzon, Ben Gibbison, Maria Pufulete (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12751364.txt.
Description
Katherine Jones and co-authors map pooled proof on drugs to prevent or treat delirium in intensive care, in a review from two thousand twenty-five. Delirium lengthens stays and raises death and mind decline. The team gathered systematic reviews of drug trials in adults in intensive care and mapped effects with proof grades.
Fifty-six reviews were found, and a drug class led by dexmedetomidine held the largest proof base. That class likely cut delirium and shortened stays versus dummy care. Proof for other drugs was mixed, and no pooled work covered mind or distress outcomes. Sedative trimming plans also lacked pooled proof. Readers get the strongest drug lead and the gaps named.
Catalog record
| CREATOR | Katherine L Jones, Burak Kundakci, Andrew Booth, Louise Falzon, Ben Gibbison, Maria Pufulete |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |