Utility of TaqMan Array Cards for detection of acute febrile illness etiologies in patients suspected of viral hemorrhagic fever infections
Gloria Grace Akurut, Luke Nyakarahuka, Shannon Whitmer, Dianah Namanya, Kilama Kamugisha, Sophia Mulei, Jimmy Baluku, Alex Tumusime, Jackson Kyondo, Ketan Patel, Julius J. Lutwama, Trevor Shoemaker, Joel Montgomery, John D. Klena, Stephen Balinandi · 2025
Read Utility of TaqMan Array Cards for detection of acute febrile illness etiologies in patients suspected of viral hemorrhagic fever infections by Gloria Grace Akurut, Luke Nyakarahuka, Shannon Whitmer, Dianah Namanya, Kilama Kamugisha, Sophia Mulei, Jimmy Baluku, Alex Tumusime, Jackson Kyondo, Ketan Patel, Julius J. Lutwama, Trevor Shoemaker, Joel Montgomery, John D. Klena, Stephen Balinandi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12751250.txt.
Description
Gloria Grace Akurut and a large team of colleagues evaluate a multi-pathogen test card for diagnosing fevers in patients first suspected of viral hemorrhagic fever. The card detects twenty-six pathogens within about two hours of extracting nucleic acids. They ran it on 182 stored samples, all hemorrhagic-fever negative, from surveillance in Uganda and neighboring countries.
Seven pathogens turned up in about a third of samples. Malaria parasites dominated, followed by salmonella species, yellow fever virus, and a few others. Assay positivity was significantly tied to whether patients lived or died. The authors conclude the card is a feasible, readily adoptable tool for national testing algorithms during fever outbreaks in sub-Saharan Africa.
Catalog record
| CREATOR | Gloria Grace Akurut, Luke Nyakarahuka, Shannon Whitmer, Dianah Namanya, Kilama Kamugisha, Sophia Mulei, Jimmy Baluku, Alex Tumusime, Jackson Kyondo, Ketan Patel, Julius J. Lutwama, Trevor Shoemaker, Joel Montgomery, John D. Klena, Stephen Balinandi |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |