βcatenin-1 localization and transcriptomic profiling provide insights into the early development of planarians
P. Coronel-Córdoba, M. Sureda-Gómez, J. M. Martín-Durán, F. Monjo, E. Saló, J. F. Abril, T. Adell · 2025
Read βcatenin-1 localization and transcriptomic profiling provide insights into the early development of planarians by P. Coronel-Córdoba, M. Sureda-Gómez, J. M. Martín-Durán, F. Monjo, E. Saló, J. F. Abril, T. Adell (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12751228.txt.
Description
Flatworms that regrow whole bodies start life in an odd way, with no neat spiral of dividing cells. Coronel-Córdoba and co-authors probed that start in this 2025 study. The species is a small planarian whose embryos feed on yolk. A signaling protein called βcatenin-1 was tracked inside cells hour by hour.
The protein first entered nuclei in yolk cells around the early embryo. By one day after egg laying it appeared in the embryo's own cells, just as movement and signaling genes switched on. Later it marked one pole, where gut and throat precursors form, and the skin lineage. Gene activity profiles matched each stage. The map clarifies a development style found nowhere else in its phylum.
Catalog record
| CREATOR | P. Coronel-Córdoba, M. Sureda-Gómez, J. M. Martín-Durán, F. Monjo, E. Saló, J. F. Abril, T. Adell |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 98 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |