Pharmacodynamics of direct oral anticoagulants associated with post-endoscopic delayed mucosal resection bleeding of colorectal neoplasms
Masaki Murata, Mitsushige Sugimoto, Satoshi Ueshima, Yasuaki Nagami, Masaki Ominami, Yohei Furumoto, Tatsuya Mikami, Manabu Sawaya, Naohisa Yoshida, Ken Inoue, Yasuhiko Maruyama, Tomohiro Terai, Shigetsugu Tsuji, Takeshi Yamamura, Takanori Yamada, Yoji Takeuchi, Nobuaki Yagi, Satoshi Osawa, Yashiro · 2025
Read Pharmacodynamics of direct oral anticoagulants associated with post-endoscopic delayed mucosal resection bleeding of colorectal neoplasms by Masaki Murata, Mitsushige Sugimoto, Satoshi Ueshima, Yasuaki Nagami, Masaki Ominami, Yohei Furumoto, Tatsuya Mikami, Manabu Sawaya, Naohisa Yoshida, Ken Inoue, Yasuhiko Maruyama, Tomohiro Terai, Shigetsugu Tsuji, Takeshi Yamamura, Takanori Yamada, Yoji Takeuchi, Nobuaki Yagi, Satoshi Osawa, Yashiro (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12749976.txt.
Description
Murata and co-authors wrote a study from 2025 on delayed bleeding after removal of bowel growths in patients on blood thinners. The drugs, a class of direct oral blood thinners, are gauged poorly by standard tests. Their strength in the blood varies a lot from person to person. Delayed bleeding days after the snip is a known risk of the procedure. Whether the drug's measured strength predicts that bleed was unknown.
Centers across Japan followed users of these drugs through the procedure over four years. About one in ten suffered delayed bleeding. Blood levels of the drugs swung widely between patients on the same dose. A lab gauge of the drug's anti-clotting action tracked the blood levels closely. In the pooled math, patients whose drug action ran high faced far greater odds of a delayed bleed. The team advises care with patients whose readings run strong.
Catalog record
| CREATOR | Masaki Murata, Mitsushige Sugimoto, Satoshi Ueshima, Yasuaki Nagami, Masaki Ominami, Yohei Furumoto, Tatsuya Mikami, Manabu Sawaya, Naohisa Yoshida, Ken Inoue, Yasuhiko Maruyama, Tomohiro Terai, Shigetsugu Tsuji, Takeshi Yamamura, Takanori Yamada, Yoji Takeuchi, Nobuaki Yagi, Satoshi Osawa, Yashiro |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |