Multidimensional plasticity of natural killer cells in tumours
Xinya Yang, Zhaoyang Song, Ligang Chen, Qingge Jia, Mingyang Li · 2025
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Description
Five authors review how natural killer cells change shape and role inside tumors, in a 2025 paper. These immune cells can kill tumor cells, but the tumor setting can blunt them. The review tracks shifts in cell markers, cell tasks, and cell fuel use. It also looks at new subsets that form in that setting.
Inside tumors, the cells gain more stop signals and lose go signals. Some become worn out, while others settle in tissue and stay there. Lack of food and waste build-up further weaken their attack. The authors weigh fixes such as built cells with sharper aim, fuel repair, and drugs that change the tumor setting. They note that tumor variety and lasting cell damage still block progress.
Catalog record
| CREATOR | Xinya Yang, Zhaoyang Song, Ligang Chen, Qingge Jia, Mingyang Li |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 69 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |