Exploring the expression and prognostic roles of LAD1 in lung adenocarcinoma

Sufen Wang, Banghong Qiang, Xiaoyan Xu, Yan Fang, Yinhua Liu, Wei Zhang, Xi Huang · 2025

Read Exploring the expression and prognostic roles of LAD1 in lung adenocarcinoma by Sufen Wang, Banghong Qiang, Xiaoyan Xu, Yan Fang, Yinhua Liu, Wei Zhang, Xi Huang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12749629.txt.

Description

Sufen Wang and co-authors probe a cell protein in lung cancer in a 2025 paper. The cancer type is lung adenocarcinoma, a common form with poor outlook. The protein, LAD1, sits in the base sheet under cells and has been tied to tumor growth.

Single cell and bulk gene reads showed LAD1 active just in cancer cells. Its levels moved with a set of genes tied to cancer spread. In tissue from thirty six patients, stains tracked LAD1 against case traits. Cutting LAD1 in lab cells changed how fast they moved and invaded. The protein may serve as a mark and a target.

Catalog record

CREATORSufen Wang, Banghong Qiang, Xiaoyan Xu, Yan Fang, Yinhua Liu, Wei Zhang, Xi Huang
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE40 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12749629

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