Percutaneous extraction using sponge spicules for disease diagnosis and therapeutic drug monitoring
Shimeng Li, Shiyan Zhang, Mengnan Jia, Siqing Chen, Ran Zhang, Yuhan Liu, Guoliang Yan, Ming Chen · 2025
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Description
Diagnostic and therapeutic drug monitoring are necessary means of precision medicine. Our previous study demonstrated that the sponge Haliclona sp. spicules (SHS) can be employed as a new class of microneedles, capable of forming a substantial number of microchannels within the skin. In this study, dermal interstitial fluid (ISF) was obtained via percutaneous extraction using sponge Haliclona sp.
Catalog record
| CREATOR | Shimeng Li, Shiyan Zhang, Mengnan Jia, Siqing Chen, Ran Zhang, Yuhan Liu, Guoliang Yan, Ming Chen |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |