High-speed 3D DNA PAINT and unsupervised clustering for unlocking 3D DNA origami cryptography

Gde Bimananda Mahardika Wisna, Daria Sukhareva, Jonathan Zhao, Prathamesh Chopade, Deeksha Satyabola, Michael Matthies, Subhajit Roy, Chao Wang, Petr Šulc, Hao Yan, Rizal F Hariadi · 2025

Read High-speed 3D DNA PAINT and unsupervised clustering for unlocking 3D DNA origami cryptography by Gde Bimananda Mahardika Wisna, Daria Sukhareva, Jonathan Zhao, Prathamesh Chopade, Deeksha Satyabola, Michael Matthies, Subhajit Roy, Chao Wang, Petr Šulc, Hao Yan, Rizal F Hariadi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12749235.txt.

Description

Eleven researchers report a study from two thousand twenty-five on hiding data inside folded DNA shapes. DNA origami folds a long DNA strand into a planned shape, and hidden patterns in the folds can store information like a code. Reading that code back fast and correctly is the hard part.

The team paired a fast imaging method, called DNA PAINT, with an automatic grouping method that needs no labels. The pairing read out two and three dimensional origami codes with accuracy up to eighty-nine percent. Simulations helped them allow for the bending of the shapes. They also set rules that promise full recovery of the stored message.

Catalog record

CREATORGde Bimananda Mahardika Wisna, Daria Sukhareva, Jonathan Zhao, Prathamesh Chopade, Deeksha Satyabola, Michael Matthies, Subhajit Roy, Chao Wang, Petr Šulc, Hao Yan, Rizal F Hariadi
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE80 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12749235

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