ALS: a field in motion
Ruben J. Cauchi, Andrew P. Tosolini · 2025
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Description
Ruben Cauchi and Andrew Tosolini introduce a journal collection on amyotrophic lateral sclerosis, a disease that kills the nerve cells controlling movement. The illness leads to paralysis and early death, and its causes mix genes, life exposures, and chance. The collection gathers studies from four continents.
Highlights include a gene variant that proved harmless in fruit flies, brain scans showing shrinkage beyond movement areas, and hints that early life exposures start a long path to disease. New animal models and a muscle test in fish also feature. Stress paths and brain reserve shape how fast the disease moves. The editors frame the illness as a whole body, whole life problem and point to shared ground with future treatments.
Catalog record
| CREATOR | Ruben J. Cauchi, Andrew P. Tosolini |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 19 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |