Exploratory evidence of mitigated immune imprinting following concomitant COVID-19 and influenza vaccination

Min Joo Choi, WonSeok Gwak, Jae Young Yun, Hae Jeon Ju, Eunjoo Choi, Hee Jin Cheong, Woo Joo Kim, Chulwoo Kim, Hwa Jung Kim, A-Yeung Jang, SunKyung Yoon, June-Woo Lee, Hye-Sook Jeong, Joon Young Song · 2025

Read Exploratory evidence of mitigated immune imprinting following concomitant COVID-19 and influenza vaccination by Min Joo Choi, WonSeok Gwak, Jae Young Yun, Hae Jeon Ju, Eunjoo Choi, Hee Jin Cheong, Woo Joo Kim, Chulwoo Kim, Hwa Jung Kim, A-Yeung Jang, SunKyung Yoon, June-Woo Lee, Hye-Sook Jeong, Joon Young Song (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12749089.txt.

Description

Min Joo Choi and co-authors study what happens when COVID-19 and flu vaccines are given at the same visit, in a paper from 2025. Giving both at once is now common practice. Long-term data on how the pairing affects immune response, above all for new virus variants, were still scarce.

Eighty adults took part and were followed for ten months. Half got both vaccines at one visit, and half got them at least four weeks apart. Blood tests tracked antibodies and the power of the response against the first virus form and a later variant. Both groups kept strong responses for the full period, with no sign that one vaccine blocked the other. The joint group showed a stronger variant response early on. The authors call that sign of eased immune imprinting, and say it needs more study.

Catalog record

CREATORMin Joo Choi, WonSeok Gwak, Jae Young Yun, Hae Jeon Ju, Eunjoo Choi, Hee Jin Cheong, Woo Joo Kim, Chulwoo Kim, Hwa Jung Kim, A-Yeung Jang, SunKyung Yoon, June-Woo Lee, Hye-Sook Jeong, Joon Young Song
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12749089

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