Revisiting the 2015 MDS diagnostic criteria for Parkinson disease: insights from autopsy-confirmed cases
Susan H Fox, Daniel G Luca, Ronald B Postuma, Roongroj Bhidayasiri, Francisco Cardoso, Gabor G Kovacs, Regina Katzenschlager, Claudia Trenkwalder · 2025
Read Revisiting the 2015 MDS diagnostic criteria for Parkinson disease: insights from autopsy-confirmed cases by Susan H Fox, Daniel G Luca, Ronald B Postuma, Roongroj Bhidayasiri, Francisco Cardoso, Gabor G Kovacs, Regina Katzenschlager, Claudia Trenkwalder (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12748991.txt.
Description
Rules for naming Parkinson disease rest on expert views from twenty fifteen, and Susan Fox and co-authors checked those rules against brain-proven cases in work from twenty twenty-five. Their review searched past studies that paired clinic notes with brain checks after death, for both true Parkinson disease and look-alike states.
Traits that back the label, such as a strong drug response and rest tremor, showed up more in true cases. Blockers and red flags showed up more in look-alike states. Yet a few flags, like fast loss of walking, did appear in a small share of true cases. Few studies held the full data such checks need, so the authors call the proof thin and urge care in how the rules are tuned next.
Catalog record
| CREATOR | Susan H Fox, Daniel G Luca, Ronald B Postuma, Roongroj Bhidayasiri, Francisco Cardoso, Gabor G Kovacs, Regina Katzenschlager, Claudia Trenkwalder |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |