Deciphering the clinical implication of an obesity-related gene signature as the novel biomarker for acute myocardial infarction diagnosis
Weixia Dong, Zixin Xue, Min Zhang, Feng Lu, Shaoping Ji · 2025
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Description
Weixia Dong and co-authors searched in 2025 for a gene sign that could help diagnose heart attack and is linked to obesity. Obesity feeds the disease, a major cause of death and disability. The team mined public gene data sets and a gene database, then used learning methods to pick key genes.
Five genes formed a sign that sorted heart attack cases well in training data and fairly well in a check set. Groups split by risk differed in immune cell types and immune functions. Lab tests confirmed the five genes differed between cases and controls. The authors offer the sign as a candidate aid for diagnosis.
Catalog record
| CREATOR | Weixia Dong, Zixin Xue, Min Zhang, Feng Lu, Shaoping Ji |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |