Genomic and functional characterization of a novel temperate Coventryvirus phage infecting Staphylococcus pseudintermedius
Patoo Withatanung, Sukanya Apiratwarrasakul, Pathomporn Sresuwadjarey, Nathita Phumthanakorn, Varintip Lerdsittikul · 2025
Read Genomic and functional characterization of a novel temperate Coventryvirus phage infecting Staphylococcus pseudintermedius by Patoo Withatanung, Sukanya Apiratwarrasakul, Pathomporn Sresuwadjarey, Nathita Phumthanakorn, Varintip Lerdsittikul (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12748576.txt.
Description
Patoo Withatanung and co-authors characterize a new virus that infects a staph bacterium in this 2025 paper. The host, Staphylococcus pseudintermedius, infects animals and can pass to humans. Drug resistant forms with strong biofilms are a growing problem. The virus, called VL4, was isolated from sewage using a resistant clinical strain.
Its genome holds 68 reading frames and no toxin, resistance, or virulence genes. Family analysis placed it as a new species in its genus. The virus reproduced fast and stayed stable at body temperature and neutral acidity. It suppressed host growth and attacked 27 of 31 clinical isolates. It also blocked new biofilms and partly broke down mature ones. Such phages may become backup treatments.
Catalog record
| CREATOR | Patoo Withatanung, Sukanya Apiratwarrasakul, Pathomporn Sresuwadjarey, Nathita Phumthanakorn, Varintip Lerdsittikul |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 59 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |