Caspase-3 deficiency inhibits the development and anti-tumor response of bone marrow-derived dendritic cells
Jinqiang Liu, Kunli Du, Yaozhen Chen, Gaozan Zheng, Hongwei Zhang, Wen Zhang, Xingbin Hu, Fan Feng · 2025
Read Caspase-3 deficiency inhibits the development and anti-tumor response of bone marrow-derived dendritic cells by Jinqiang Liu, Kunli Du, Yaozhen Chen, Gaozan Zheng, Hongwei Zhang, Wen Zhang, Xingbin Hu, Fan Feng (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12748387.txt.
Description
This study investigated the impact of Caspase-3 gene deletion on bone marrow-derived dendritic cells (BMDCs) and their anti-tumor functions. BMDCs were generated in vitro using GM-CSF and IL-4 from Caspase-3 knockout (Casp3-KO) and heterozygous (Heter) mouse progenitors. Caspase-3 ablation reduced dendritic cell numbers in vivo and hindered BMDC generation in vitro.
Catalog record
| CREATOR | Jinqiang Liu, Kunli Du, Yaozhen Chen, Gaozan Zheng, Hongwei Zhang, Wen Zhang, Xingbin Hu, Fan Feng |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |