Mixed phenotype acute leukemia, the dissection of an enigmatic disease in the era of novel therapies
Magdalena Karasek, Izabela Kubiszewska, Marta Sobas · 2025
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Description
Magdalena Karasek, Izabela Kubiszewska, and Marta Sobas review a rare and mixed form of acute leukemia. Their paper is from two thousand twenty-five. In this disease, the cancer blasts bear marks of more than one cell line at once. That mix makes it hard to name and hard to treat, and results are poor on the whole.
They sum up how the disease is defined, split by gene marks, and treated. Two mixes rule: one joins B-cell and myeloid marks, the other T-cell and myeloid. Gene faults are found in most cases. No standard care path exists. Plans built for lymphoid leukemia give the best results so far, and stem cell transplants stay key. New targeted drugs are in view.
Catalog record
| CREATOR | Magdalena Karasek, Izabela Kubiszewska, Marta Sobas |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |