Editorial: Macrophages: allies or merciless enemies in musculoskeletal systems
M. Alaa Terkawi, Ken Kadoya, Tsutomu Endo · 2025
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Description
Terkawi, Kadoya, and Endo wrote a 2025 editorial on immune cells called macrophages in muscle, bone, and joint disease. These diseases, from worn joints to bone loss, limit movement and quality of life. Current drugs often fail to rebuild tissue, so the editors argue research must learn how the body keeps and repairs its own tissues.
Macrophages can help repair or drive harm, shifting states with local cues. The old two-state model now looks too simple, the editors note, since single-cell scans show a smooth range of states. Their special issue gathers four reviews and one research paper on these cells in health, repair, and disease.
Catalog record
| CREATOR | M. Alaa Terkawi, Ken Kadoya, Tsutomu Endo |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 9 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |