Identification of exosome miRNAs regulated by SPHK2 in human glioma cells
Jing Liu, Huafu Zhao, Xia Liu, Xiaoyun Guan, Qiyu Guo, Yanwen Xu, Jinhua Qiu · 2025
Read Identification of exosome miRNAs regulated by SPHK2 in human glioma cells by Jing Liu, Huafu Zhao, Xia Liu, Xiaoyun Guan, Qiyu Guo, Yanwen Xu, Jinhua Qiu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12747937.txt.
Description
Jing Liu and co-authors trace how a fat related enzyme steers the tiny RNA parcels that glioma cells shed, in a 2025 study. Glioma is the most common brain tumor, and its worst grade kills fast. Nearby immune cells of one type help the tumor grow, and the enzyme had been tied to that help.
The team silenced the enzyme in a human glioma cell line and read the RNA cargo of shed parcels. Twelve small RNAs shifted, two up and ten down. Their target genes mapped to more than a hundred function terms and to known pathways. The work names cargo that may push immune cells toward the tumor friendly state.
Catalog record
| CREATOR | Jing Liu, Huafu Zhao, Xia Liu, Xiaoyun Guan, Qiyu Guo, Yanwen Xu, Jinhua Qiu |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |