Encephalitis and Immune‐Related Complications in a Patient Treated With Nivolumab: A Case Report

Georgios Lyras, Prokopios Karydis, Sofia Dionysia Tetradi, Aikaterini Maria Lechouriti, Charalampos Potsios, Dimitra Taprantzi, Christos Michailides, Dimitrios Velissaris · 2025

Read Encephalitis and Immune‐Related Complications in a Patient Treated With Nivolumab: A Case Report by Georgios Lyras, Prokopios Karydis, Sofia Dionysia Tetradi, Aikaterini Maria Lechouriti, Charalampos Potsios, Dimitra Taprantzi, Christos Michailides, Dimitrios Velissaris (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12747856.txt.

Description

Georgios Lyras and co-authors report brain inflammation and other immune side effects in a cancer patient on nivolumab, in a 2025 case. The drug frees the immune system to attack cancer, but it can also turn that system on healthy tissue in many unlike ways. The patient had spread kidney cancer and was on a paired therapy.

A woman aged fifty five came in with confusion, disorientation, and low blood pressure. Brain scans showed new bright lesions, and a wide workup pointed to the drug as the cause. Steroids and antibody infusions brought rapid improvement, and a further targeted drug led to near full recovery of nerve symptoms. Other glands were hit as well.

Catalog record

CREATORGeorgios Lyras, Prokopios Karydis, Sofia Dionysia Tetradi, Aikaterini Maria Lechouriti, Charalampos Potsios, Dimitra Taprantzi, Christos Michailides, Dimitrios Velissaris
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE28 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12747856

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