Adaptive Glomerular Hypertrophy in Kidney Transplants Associated With Focal Segmental Glomerulosclerosis: Report of Three Cases
Autumn LaRocque, Ujwal Gautam, Nora Ewis, Richard Ugarte, Emily Daniel, John C. Papadimitriou, Abdolreza Haririan, Cinthia B. Drachenberg · 2025
Read Adaptive Glomerular Hypertrophy in Kidney Transplants Associated With Focal Segmental Glomerulosclerosis: Report of Three Cases by Autumn LaRocque, Ujwal Gautam, Nora Ewis, Richard Ugarte, Emily Daniel, John C. Papadimitriou, Abdolreza Haririan, Cinthia B. Drachenberg (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12747116.txt.
Description
Kidney transplant filters often grow larger to handle the extra work, but oversized filters can also signal harmful scarring disease. Autumn LaRocque and co-authors report three transplant cases in this 2025 paper where filter growth and that disease appeared together. They compared filter size in donor tissue taken before transplant with later biopsies.
Mean filter diameter was measured at each point and set against standard biopsy scores and each patient course. Growth that helps at first may turn harmful when it outpaces what the kidney can sustain. Sorting helpful growth from harmful growth is hard on standard scores alone. Three cases cannot settle the question, but they sharpen what pathologists should track in follow-up biopsies.
Catalog record
| CREATOR | Autumn LaRocque, Ujwal Gautam, Nora Ewis, Richard Ugarte, Emily Daniel, John C. Papadimitriou, Abdolreza Haririan, Cinthia B. Drachenberg |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |