Association Between Reproductive Lifespan and All-Cause and Cardiovascular Mortality in Women Aged 65 Years and Older: A Cohort Study Using NHANES 1999–2018 Data
Xiaohui Chen, Chunxue Li, Yue Bai, Lin Li · 2025
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Description
Xiaohui Chen and co-authors ask whether a longer reproductive life predicts lower death rates in older women, in a 2025 study. The data came from a national US health survey spanning 1999 to 2018, covering 4,514 postmenopausal women aged 65 and over. Reproductive lifespan counts the years from first period to menopause.
Over a median follow-up of about eight years, 39 percent died, a tenth of them from cardiovascular causes. Each extra reproductive year came with about one percent lower overall mortality in the fully adjusted model, in a straight-line pattern. The heart-death relationship took a different shape, the authors report. They frame reproductive history as one more clue in healthy-aging risk profiles.
Catalog record
| CREATOR | Xiaohui Chen, Chunxue Li, Yue Bai, Lin Li |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |