The gastrointestinal endothelin system: receptors, cellular actions, and involvement in gastrointestinal disorders
Arjun Singh, Rajvir Singh · 2025
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Description
Arjun Singh and Rajvir Singh review the gut hormone system built around endothelin in a 2025 paper. The system helps run gut motion, fluid release, feeling, and swelling. One signal, endothelin-1, acts through two kinds of locks on many gut cells, and faults in the system show up in gut ills.
Too much of the signal and too much action at one lock can drive swelling, pain, weak gut lining, and stiff muscle. Drugs that block the locks may ease such ills, the authors note. Gaps remain on which cells send which signals, so the review maps what is known and what still needs work.
Catalog record
| CREATOR | Arjun Singh, Rajvir Singh |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |