Cyclooxygenase-2 and von Willebrand factor—an immunohistochemical study of the equine foot with and without laminitis, post-mortem perfused with paraffin oil
Bianca A. Underberg, Elke Van der Vekens, Barbara Drews, Sabine Kaessmeyer · 2025
Read Cyclooxygenase-2 and von Willebrand factor—an immunohistochemical study of the equine foot with and without laminitis, post-mortem perfused with paraffin oil by Bianca A. Underberg, Elke Van der Vekens, Barbara Drews, Sabine Kaessmeyer (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12745387.txt.
Description
Bianca Underberg and co-authors built lab staining methods for horse feet in this 2025 study. Laminitis is a painful foot disease in horses with swelling and blood vessel change. The team wanted reliable stains for one swelling marker and one vessel marker in feet kept after death with paraffin oil.
They used 12 front limbs from eight horses, with and without the disease, in fresh, frozen, and perfused groups. After tuning the method, both stains worked in all groups. Shorter wax time and a tilted set in the block gave cleaner cuts. The swelling marker was much higher in diseased feet, and the vessel marker showed squeezed and widened vessels there.
Catalog record
| CREATOR | Bianca A. Underberg, Elke Van der Vekens, Barbara Drews, Sabine Kaessmeyer |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |