Alterations in the Gut Microbiome in Ankylosing Spondylitis and Their Correlation with Disease Activity
Hyemin Jeong, Hoonhee Seo, Sukyung Kim, Md Abdur Rahim, Indrajeet Barman, Md Sarower Hossen Shuvo, Sujin Jo, Mohammed Solayman Hossain, Jeong-Ju Yoo, Young Ho Kim, Sung-Soo Jung, Ho-Yeon Song, Chan Hong Jeon · 2025
Read Alterations in the Gut Microbiome in Ankylosing Spondylitis and Their Correlation with Disease Activity by Hyemin Jeong, Hoonhee Seo, Sukyung Kim, Md Abdur Rahim, Indrajeet Barman, Md Sarower Hossen Shuvo, Sujin Jo, Mohammed Solayman Hossain, Jeong-Ju Yoo, Young Ho Kim, Sung-Soo Jung, Ho-Yeon Song, Chan Hong Jeon (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12740847.txt.
Description
Hyemin Jeong and a large team of co-authors published this microbiome study in 2025 on ankylosing spondylitis, a long-lasting inflammatory disease of the spine. Gut microbes are suspected of feeding the immune dysfunction behind it. The team sequenced stool samples from 44 patients and 50 healthy controls, then compared the microbial mixes and checked them against how active each patient's disease was.
Overall diversity was similar between patients and controls, but the mix differed. Patients carried more Proteobacteria, including Escherichia types, and fewer of several groups seen as beneficial. Among patients, those with highly active disease had lower gut diversity than those with quiet disease. One genus, Coprobacter, rose in step with two standard disease activity scores. The authors suggest it as a possible marker for tracking the disease.
Catalog record
| CREATOR | Hyemin Jeong, Hoonhee Seo, Sukyung Kim, Md Abdur Rahim, Indrajeet Barman, Md Sarower Hossen Shuvo, Sujin Jo, Mohammed Solayman Hossain, Jeong-Ju Yoo, Young Ho Kim, Sung-Soo Jung, Ho-Yeon Song, Chan Hong Jeon |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |