Lifestyle Modify Optic Nerve Injury in Mendelian Randomization

Maobin Zhou, Yanyu Shangguan, Xiaodong Liu, Yaying Sun · 2025

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Description

Maobin Zhou and colleagues published a 2025 genetics study on lifestyle and optic nerve damage. The optic nerve carries vision signals to the brain. Its damage causes permanent sight loss. The team used genetic data as a natural experiment. This method tests cause better than simple observation.

Leisure screen time raised glaucoma risk in their analysis. Moderate to vigorous activity lowered the risk. The links held after adjusting for other factors. Those factors included weight, smoking, and blood sugar. Gene pathway analysis added supporting detail. The authors are careful: genetics suggests, but does not prove, daily-life effects. Still, activity looks protective for the nerve.

Catalog record

CREATORMaobin Zhou, Yanyu Shangguan, Xiaodong Liu, Yaying Sun
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE27 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12740456

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