Validated Erythrosin B spectrofluorimetric method for ganciclovir bioanalysis in rabbit plasma following valganciclovir bioconversion and Pharmacokinetic application
Ali Alqahtani, Taha Alqahtani, Adil Alshehri, Ahmed A Almrasy · 2025
Read Validated Erythrosin B spectrofluorimetric method for ganciclovir bioanalysis in rabbit plasma following valganciclovir bioconversion and Pharmacokinetic application by Ali Alqahtani, Taha Alqahtani, Adil Alshehri, Ahmed A Almrasy (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12739150.txt.
Description
Ali Alqahtani and co-authors validate in 2025 a glow-based method to measure an antiviral drug in rabbit plasma. The drug forms after a prodrug converts in the body, so plasma checks track real exposure. The method rests on dimming of a dye glow when the drug binds it.
Heat tests show the binding is static, with a one-to-one match ratio. Best runs use a set acidity, dye level, and five-minute wait. The response stays straight across the test range with a near-perfect fit score. Quantum math points to halogen links and charge pulls as the grip forces.
Catalog record
| CREATOR | Ali Alqahtani, Taha Alqahtani, Adil Alshehri, Ahmed A Almrasy |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 69 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |