IFN-γ and IL-4 correlate with protection induced by an attenuated malaria vaccine
Tanisha M. Robinson, Jessica S. Bolton, Elisabeth H. Duncan, Elke S. Bergmann-Leitner, Marie Mura · 2025
Read IFN-γ and IL-4 correlate with protection induced by an attenuated malaria vaccine by Tanisha M. Robinson, Jessica S. Bolton, Elisabeth H. Duncan, Elke S. Bergmann-Leitner, Marie Mura (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12739113.txt.
Description
A malaria vaccine made of weakened parasites, given by mosquito bite, protects some volunteers in full, and blood clues may explain who. Tanisha Robinson and co-authors studied volunteers in controlled malaria cases after such immunization. They checked immune cells in the blood and how blood cells answered parasite matter in a dish. Two signals stood out with protection. One was interferon-gamma release on meeting the parasite. The other was interleukin-4 release after the vaccine, joined by a certain T cell pattern.
Catalog record
| CREATOR | Tanisha M. Robinson, Jessica S. Bolton, Elisabeth H. Duncan, Elke S. Bergmann-Leitner, Marie Mura |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |