Development of a 3D-printable bioactive polycaprolactone–collagen peptides filament for biomedical applications

Stefano Cantella, Silvia Badini, Carlotta Bollati, Mushtaq Alam Madar Saheb, Roberto Viganò, Carmen Lammi, Raffaele Pugliese, Serena Graziosi · 2025

Read Development of a 3D-printable bioactive polycaprolactone–collagen peptides filament for biomedical applications by Stefano Cantella, Silvia Badini, Carlotta Bollati, Mushtaq Alam Madar Saheb, Roberto Viganò, Carmen Lammi, Raffaele Pugliese, Serena Graziosi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12738878.txt.

Description

Stefano Cantella and seven co-authors make a 3D-printing filament that mixes a common plastic with collagen peptides, in a research paper from 2025. The plastic, PCL, is used in medical implants but has no biological activity of its own. Collagen peptides could add that activity for healing tissues.

The team blended the materials without toxic solvents and extruded them on a custom desktop system. Tests confirmed the plastic kept its core structure and heat traits, while the peptides added stiffness and biological benefit. The material printed into lattice scaffolds, broke down at a tunable rate, and proved friendly to cells. Both fresh and recycled plastic worked as the base.

Catalog record

CREATORStefano Cantella, Silvia Badini, Carlotta Bollati, Mushtaq Alam Madar Saheb, Roberto Viganò, Carmen Lammi, Raffaele Pugliese, Serena Graziosi
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE66 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12738878

Browse the full library · About the Tower of Babel