Phytochemical investigation and antibacterial activities of Cordia africana roots extracts
Gadise Tolesa Sharge, Tegene Tesfaye Tole · 2025
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Description
Gadise Tolesa Sharge and Tegene Tesfaye Tole published a 2025 study of the roots of Cordia africana, a tree long used in folk medicine. Traditional use treats malaria, liver diseases, stomachaches, and diarrhea with it. What the root contains, and how it fights bacteria, had not been reported. The team set out to fill both gaps.
Dried root was soaked in set solvent baths, in a fixed sequence, to draw its compounds out. Screening found five kinds of plant compound in the extracts, and one known kind was absent. Two pure compounds were then separated by a column technique and identified with large laboratory instruments. The extracts and the pure compounds were tested against four kinds of bacteria on plates. One pure compound and one extract held bacteria back almost as well as a known drug, against one difficult bacterial species.
Catalog record
| CREATOR | Gadise Tolesa Sharge, Tegene Tesfaye Tole |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |