Immune Modulation in the Tumor Microenvironment: Bifurcation Analysis of Cancer-CTL-Monocyte Dynamics
Eymard Hernandez-Lopez, Russell Milne, Xiunan Wang · 2025
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Description
Hernandez-Lopez, Milne, and Wang built a math model in twenty twenty-five of how cancer cells, killer T cells, and a blood cell kind act in a tumor's zone. The blood cells can wake killer cells by wear-ing tumor marks on their skin. The model tracks growth, waning, and that wake act in linked rules.
They find the steady states, test which hold, and map where the system flips form. The wake rate from blood cells is the key knob in that map. High wake can tip the zone to clear the tumor, while low wake lets it grow. Maps of flip zones may guide paired drug care.
Catalog record
| CREATOR | Eymard Hernandez-Lopez, Russell Milne, Xiunan Wang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 225 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |