Primary Pericardial Well-Differentiated Papillary Mesothelioma in a Spotted Hyena (Crocuta crocuta)

Louise van der Weyden, Dewald Keet, Nicolize O’Dell, Ryou Tanaka · 2025

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Description

Louise van der Weyden and co-authors report a rare heart-sac tumor in a captive spotted hyena, published in 2025. Reports of tumors in hyenas are few. The adult female developed loss of appetite, lethargy, and a swollen belly over three days, and was sedated for examination, but died before internal checks could be done.

Post-mortem study found bloody fluid filling the sac around the heart, plus congestion in lungs and liver. Microscopy of the sac's surface showed fibrous growths lined by a layer of large tumor cells of mesothelial origin, forming finger-like projections and invading nearby tissue, with signs of older bleeding. The diagnosis was a well-differentiated papillary mesothelioma of the pericardium. Death was attributed to shock from the fluid pressure strangling the heart.

Catalog record

CREATORLouise van der Weyden, Dewald Keet, Nicolize O’Dell, Ryou Tanaka
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE23 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12737775

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