Does Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Represent a Poly-Herpesvirus Post-Virus Infectious Disease?
Maria Eugenia Ariza, Irene Mena Palomo, Marshall V Williams, Clinton Jones · 2025
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Description
Maria Eugenia Ariza and co-authors argue, in a 2025 review, that a long-lasting fatigue illness may be driven by several herpesviruses acting together. The illness, known as ME/CFS, disables millions worldwide and often starts after flu-like symptoms. Yet no single virus has been proven to cause it. Herpesviruses live in the body for life, switching between quiet latency and active copying.
The review focuses on a third, messier state: abortive copying, where the virus starts to reactivate but does not finish. The authors suggest this stalled activity could keep the immune system inflamed and drive symptoms. If several herpesviruses can each do this, hunting one culprit would miss the picture. They frame the illness as a possible poly-herpesvirus condition and call for studies designed to test that idea directly.
Catalog record
| CREATOR | Maria Eugenia Ariza, Irene Mena Palomo, Marshall V Williams, Clinton Jones |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |