Molecular Surveillance Reveals F-Gene Mutations and Constrained G-Gene Evolution in Human Respiratory Syncytial Virus: Implications for Vaccine Efficacy in Saudi Arabia
Mohamed A. Farrag, Ibrahim M. Aziz, Abdulaziz M. Almuqrin, Noorah A. Alkubaisi, Reem M. Aljowaie, Asma N. Alsaleh, Fatimah N. Alanazi, Adel A. Abdulmanea, Fahad N. Almajhdi · 2025
Read Molecular Surveillance Reveals F-Gene Mutations and Constrained G-Gene Evolution in Human Respiratory Syncytial Virus: Implications for Vaccine Efficacy in Saudi Arabia by Mohamed A. Farrag, Ibrahim M. Aziz, Abdulaziz M. Almuqrin, Noorah A. Alkubaisi, Reem M. Aljowaie, Asma N. Alsaleh, Fatimah N. Alanazi, Adel A. Abdulmanea, Fahad N. Almajhdi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12737416.txt.
Description
Mohamed Farrag and co-authors tracked a common child virus in Saudi Arabia in a 2025 study. The virus, RSV, is a top cause of serious lung infections in young children, and new vaccines now target its F protein, so watching the virus change is vital.
The team tested 200 nose samples from sick children in Riyadh and sequenced key genes from the positives. RSV turned up in about one in seven samples, with type B slightly ahead of type A. Babies aged two to five months were hit most often. The F gene showed mutations while the G gene changed little, a pattern vaccine planners need to watch.
Catalog record
| CREATOR | Mohamed A. Farrag, Ibrahim M. Aziz, Abdulaziz M. Almuqrin, Noorah A. Alkubaisi, Reem M. Aljowaie, Asma N. Alsaleh, Fatimah N. Alanazi, Adel A. Abdulmanea, Fahad N. Almajhdi |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |