Multifunctional Bilayer Wound Dressing Composed of Immediate Release Layer of Ofloxacin and Sustained Release Layer of Bergamot Oil
Mehar Un Nisa, Ikram Ullah Khan, Yousaf Kamal, Usra, Zunera Chaudhary, Ghulam Hussain, Muhammad Irfan, Syed Haroon Khalid, Sajid Asghar, Hafeez Ullah Khan, Safirah Maheen, Syed Adnan Ali Shah, Thierry F. Vandamme · 2025
Read Multifunctional Bilayer Wound Dressing Composed of Immediate Release Layer of Ofloxacin and Sustained Release Layer of Bergamot Oil by Mehar Un Nisa, Ikram Ullah Khan, Yousaf Kamal, Usra, Zunera Chaudhary, Ghulam Hussain, Muhammad Irfan, Syed Haroon Khalid, Sajid Asghar, Hafeez Ullah Khan, Safirah Maheen, Syed Adnan Ali Shah, Thierry F. Vandamme (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12736944.txt.
Description
Mehar Un Nisa and co-authors craft a two-layer wound dressing that fires its antibiotic fast, then keeps soothing for days. Skin itself is bilayered, and dressings that mimic it heal better. One layer must kill bacteria immediately; the other should release its payload slowly as tissue rebuilds.
Using double solvent casting, they built a base layer of sodium alginate releasing bergamot essential oil in a sustained way, topped by a cellulose layer that dumps ofloxacin at once. Laboratory characterization checked the films' structure and release behavior. Such staged pharmacology in a single bandage could cut dressing changes and infections in the chronic wounds that stall in clinics and homes alike.
Catalog record
| CREATOR | Mehar Un Nisa, Ikram Ullah Khan, Yousaf Kamal, Usra, Zunera Chaudhary, Ghulam Hussain, Muhammad Irfan, Syed Haroon Khalid, Sajid Asghar, Hafeez Ullah Khan, Safirah Maheen, Syed Adnan Ali Shah, Thierry F. Vandamme |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 58 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |