Flavonifractor plautii as a Next-Generation Probiotic Enhancing the NGP F/P Index in a Simulated Human Gut Microbiome Ecosystem
Md Sarower Hossen Shuvo, Sukyung Kim, Sujin Jo, Md Abdur Rahim, Indrajeet Barman, Mohammed Solayman Hossain, Youjin Yoon, Hanieh Tajdozian, Izaz Ahmed, Ali Atashi, GangWon Jeong, Ho-Seong Suh, JiMin You, Chaemin Sung, Mijung Kim, Hoonhee Seo, Ho-Yeon Song, Ivana Cacciatore · 2025
Read Flavonifractor plautii as a Next-Generation Probiotic Enhancing the NGP F/P Index in a Simulated Human Gut Microbiome Ecosystem by Md Sarower Hossen Shuvo, Sukyung Kim, Sujin Jo, Md Abdur Rahim, Indrajeet Barman, Mohammed Solayman Hossain, Youjin Yoon, Hanieh Tajdozian, Izaz Ahmed, Ali Atashi, GangWon Jeong, Ho-Seong Suh, JiMin You, Chaemin Sung, Mijung Kim, Hoonhee Seo, Ho-Yeon Song, Ivana Cacciatore (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12736906.txt.
Description
Shuvo and co-authors published a 2025 study of a gut bacterium, Flavonifractor plautii, as a candidate next-generation probiotic. Standard probiotics rely on a small set of well-worn strains, so new candidates are in demand. The team isolated the strain from human feces, read its full genome, and named it PMC93. They then dosed a lab system that mimics the human gut ecosystem, daily for one week.
The strain did not disturb the overall mix of gut microbes, a good safety sign. It raised the ratio of one large bacterial group to another, a score the team tracks, beyond what standard probiotics achieved. Helpful groups that make short-chain fatty acids grew, while harmful groups shrank. The strain also passed safety tests in animals. The authors present it as a promising candidate for gut health products.
Catalog record
| CREATOR | Md Sarower Hossen Shuvo, Sukyung Kim, Sujin Jo, Md Abdur Rahim, Indrajeet Barman, Mohammed Solayman Hossain, Youjin Yoon, Hanieh Tajdozian, Izaz Ahmed, Ali Atashi, GangWon Jeong, Ho-Seong Suh, JiMin You, Chaemin Sung, Mijung Kim, Hoonhee Seo, Ho-Yeon Song, Ivana Cacciatore |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 70 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |