PEGylated Terpesome-Loaded 3D-Printed Aripiprazole Ocuserts for the Treatment of Ocular Candidiasis
Rofida Albash, Mariam Hassan, Ahmed M. Agiba, Wessam H. Abd-Elsalam, Diana Aziz, Youssef R. Hassan, Amira B. Kassem, Asmaa Saleh, Moaz A. Eltabeeb · 2025
Read PEGylated Terpesome-Loaded 3D-Printed Aripiprazole Ocuserts for the Treatment of Ocular Candidiasis by Rofida Albash, Mariam Hassan, Ahmed M. Agiba, Wessam H. Abd-Elsalam, Diana Aziz, Youssef R. Hassan, Amira B. Kassem, Asmaa Saleh, Moaz A. Eltabeeb (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12736843.txt.
Description
A drug used for psychosis may also fight a fungal infection of the eye, if it can be delivered well. Rofida Albash and co-authors report a 2025 effort to package that drug, aripiprazole, into tiny carriers placed in the eye.
The team loaded the drug into small fatty bubbles coated for longer action, then set them into printed inserts made of a plant-based plastic. Tests showed the bubbles were tiny, stable, and stuck well to the eye surface. In rabbits with a fungal cornea infection, the insert gave a strong healing effect, and tissue checks showed no harm. The work pairs drug reuse with printed delivery in a fresh way.
Catalog record
| CREATOR | Rofida Albash, Mariam Hassan, Ahmed M. Agiba, Wessam H. Abd-Elsalam, Diana Aziz, Youssef R. Hassan, Amira B. Kassem, Asmaa Saleh, Moaz A. Eltabeeb |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |