Co-Amorphous Systems Based on Dihydroquercetin and l-Lysine: Synthesis and Evaluation

Artem A Svotin, Maria D Korochkina, Anastasia A Khodyachikh, Diana R Kolesnikova, Amir Taldaev, Eduard V Bocharov, Alexander V Dzuban, Andrey N Utenyshev, Gennadii V Shilov, Youyan Zeng, Bo Li, Roman P Terekhov, Irina A Selivanova, Peter Timmins, Kyriakos Kachrimanis · 2025

Read Co-Amorphous Systems Based on Dihydroquercetin and l-Lysine: Synthesis and Evaluation by Artem A Svotin, Maria D Korochkina, Anastasia A Khodyachikh, Diana R Kolesnikova, Amir Taldaev, Eduard V Bocharov, Alexander V Dzuban, Andrey N Utenyshev, Gennadii V Shilov, Youyan Zeng, Bo Li, Roman P Terekhov, Irina A Selivanova, Peter Timmins, Kyriakos Kachrimanis (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12736791.txt.

Description

A peer-reviewed research article from Europe PMC (2025). Background/Objectives: Dihydroquercetin (DHQ), also known as taxifolin, is a natural flavonoid which has anti-inflammatory and wound-healing biological effects. One of the main limitations for developing formulations with DHQ is its low solubility in water at room temperature. One of the high-potential co-formers for increasing its solubility is l-lysine, which has an aliphatic amino group in the side radical capable of entering into intermolecular interactions with the phenolic hydroxyl groups of DHQ. Methods: Several modifications were obtained using grinding, drying, and lyophilization methods.

Catalog record

CREATORArtem A Svotin, Maria D Korochkina, Anastasia A Khodyachikh, Diana R Kolesnikova, Amir Taldaev, Eduard V Bocharov, Alexander V Dzuban, Andrey N Utenyshev, Gennadii V Shilov, Youyan Zeng, Bo Li, Roman P Terekhov, Irina A Selivanova, Peter Timmins, Kyriakos Kachrimanis
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE46 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12736791

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