Nisin or Chitosan Enhance the Antimicrobial Activity of Ceftiofur Against Antibiotic-Resistant Staphylococcus aureus and Have Antibiofilm Effects
Mónica G. Sánchez-Ceja, Jaime L. Esquivel-Alejo, Ricardo I. Medina-Estrada, Rafael Jiménez-Mejía, Gustavo Santoyo, Joel E. López-Meza, Pedro D. Loeza-Lara · 2025
Read Nisin or Chitosan Enhance the Antimicrobial Activity of Ceftiofur Against Antibiotic-Resistant Staphylococcus aureus and Have Antibiofilm Effects by Mónica G. Sánchez-Ceja, Jaime L. Esquivel-Alejo, Ricardo I. Medina-Estrada, Rafael Jiménez-Mejía, Gustavo Santoyo, Joel E. López-Meza, Pedro D. Loeza-Lara (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12736378.txt.
Description
Mónica Sánchez-Ceja and co-authors pair natural agents with an antibiotic against a cow udder germ in a 2025 study. Mastitis, an udder infection, costs dairy farms worldwide. The germ at issue shrugs off the standard drug and builds slime shields called biofilms.
Two helpers were tested: nisin, a germ-made peptide, and chitosan, a shell-derived polymer. At low doses, each boosted the drug's power against two farm strains and a lab strain. The chitosan mix worked best of all. Stain and live-count tests showed the pairs also broke into pre-made biofilms and killed cells inside. The authors pitch the pairs as aids to prevent or control mastitis with less drug.
Catalog record
| CREATOR | Mónica G. Sánchez-Ceja, Jaime L. Esquivel-Alejo, Ricardo I. Medina-Estrada, Rafael Jiménez-Mejía, Gustavo Santoyo, Joel E. López-Meza, Pedro D. Loeza-Lara |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |