Propolis Exerts Antibiofilm Activity Against Methicillin-Resistant Staphylococcus aureus by Modulating Gene Expression to Suppress Adhesion

He Sang, Kaiyue Feng, Yanhu Ju, Yueying Sun, Yang Zhang, Hongzhuan Xuan, Fei Wang · 2025

Read Propolis Exerts Antibiofilm Activity Against Methicillin-Resistant Staphylococcus aureus by Modulating Gene Expression to Suppress Adhesion by He Sang, Kaiyue Feng, Yanhu Ju, Yueying Sun, Yang Zhang, Hongzhuan Xuan, Fei Wang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12736273.txt.

Description

He Sang and co-authors present a 2025 lab study of propolis, a resin bees make, against a drug-resistant staph germ known as MRSA. The germ resists many drugs and often infects patients in care settings. It also builds biofilms, slimy layers that shield it from treatment, so new anti-biofilm options are in demand.

An alcohol extract of propolis stopped both test strains at the same dose. Staining and cell tests showed the extract blocked new biofilm growth and shrank films already formed, and microscope images showed fewer germs sticking to surfaces. Gene tests showed the extract turned down genes the germ uses to attach and build its film.

Catalog record

CREATORHe Sang, Kaiyue Feng, Yanhu Ju, Yueying Sun, Yang Zhang, Hongzhuan Xuan, Fei Wang
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12736273

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