The Aromatic Amino Acid Biosynthesis Gene VdARO2 and the Cross-Pathway Regulator VdCPC1 Coordinately Regulate Virulence in Verticillium dahliae
Chongbo Zhang, Can Xu, Yuan Wang, Jiafeng Huang, Xiaoqiang Zhao, JH de Winde · 2025
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Description
Chongbo Zhang and co-authors study, in twenty twenty-five, two genes that jointly control virulence in a soil fungus that wilts cotton. The fungus, Verticillium dahliae, causes major cotton losses. One gene helps build aromatic amino acids, the building blocks with ring structures. The other is a master regulator of the amino acid starvation response. The team deleted or silenced each gene and watched growth, spore making, and the hard resting structures the fungus forms in soil.
Both genes proved essential for growth, spore making, and resting structure formation. Deleting the first gene caused severe defects and a total loss of resting structures. It also switched the second gene into overdrive, a starvation response that failed to restore virulence.
Catalog record
| CREATOR | Chongbo Zhang, Can Xu, Yuan Wang, Jiafeng Huang, Xiaoqiang Zhao, JH de Winde |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |