The Role of Vitamin D in Parkinson’s Disease: Evidence from Serum Concentrations, Supplementation, and VDR Gene Polymorphisms
Jamir Pitton Rissardo, Ana Leticia Fornari Caprara · 2025
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Description
Jamir Pitton Rissardo and Ana Leticia Fornari Caprara review the role of vitamin D in Parkinson's disease in a 2025 paper. The vitamin is thought to protect nerve cells, but its link to this disease has stayed murky. The review joins blood level studies, supplement trials, and gene studies in one synthesis.
Across sixty-three studies with roughly ten thousand people, patients had clearly lower vitamin D levels than healthy adults. Lack of the vitamin was more common among patients, and ample levels linked to a modestly lower risk of the disease. Supplements gave small, non-significant gains in movement scores. One variant in the vitamin's receptor gene linked to the disease most steadily. The authors call for care in judging cause and effect.
Catalog record
| CREATOR | Jamir Pitton Rissardo, Ana Leticia Fornari Caprara |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 68 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |