Neuroprotective Effect of Fresh Gac Fruit Parts Against β-Amyloid-Induced Toxicity and Its Influence on Synaptic Gene Expression in HT-22 Cell Model
Asif Ali, Chih-Li Lin, Chin-Kun Wang · 2025
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Description
Ali, Lin, and Wang test gac fruit extracts for nerve protection in a cell model. Brain degeneration illness rises fast as populations age. Costs and caregiver load rise with that trend as well. Gac fruit is rich in active compounds and used as food and folk medicine.
Past work showed gac aids memory and clears amyloid in models. The team made extracts from fresh fruit parts with varied solvents. Lab nerve cells were exposed to amyloid toxin for tests. Extracts were checked for cell survival after that exposure. Gene use for synapse function was also gauged. Results may point to food-based nerve aids.
Catalog record
| CREATOR | Asif Ali, Chih-Li Lin, Chin-Kun Wang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |